Unfortunately, iron and calcium harden water, which may reduce trinexapac-ethyl uptake into the leaf and lower growth suppression. 5. %PDF-1.6 % Lose the iron and calcium. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. Trade name Tweak Yield and Quality Enhancer Other names: Trinexapac-ethyl 250 g/L EC, CHA 8830 Product Use: Improves the percent of thebaine in Poppies. Once a pesticide's toxicological profile is determined, EPA identifies toxicological points of departure (POD) and levels of concern (LOC) to use in evaluating the risk posed by human exposure to the pesticide. The authority citation for part 180 continues to read as follows: Authority: Based on the lack of evidence of carcinogenicity in two adequate rodent carcinogenicity studies, trinexapac-ethyl is not expected to pose a cancer risk to humans. Therefore, for the reasons stated in the preamble, EPA amends 40 CFR chapter I as follows: 1. You must file your objection or request a hearing on this regulation in accordance with the instructions provided in 40 CFR part 178. 3501 et seq. Prevent further spillage or leakage if it is safe to do so. Registration Review. Trinexapac-ethyl is approved for use on cereal crops such as barley, durum wheat, oats, rye, triticale and wheat as well as grassland, amenity turf and managed turf. Trinexapac-ethyl; tolerances for residues. Because this action has been exempted from review under Executive Order 12866, this action is not subject to Executive Order 13211, entitled Actions Concerning Regulations That Significantly Affect Energy Supply, Distribution, or Use (66 FR 28355, May 22, 2001) or Executive Order 13045, entitled Protection of Children from Environmental Health Risks and Safety Risks (62 FR 19885, April 23, 1997), nor is it considered a regulatory action under Executive Order 13771, entitled Reducing Regulations and Controlling Regulatory Costs (82 FR 9339, February 3, 2017). the material on FederalRegister.gov is accurately displayed, consistent with Chemical Review Manager: Kylie Rothwell (rothwell.kylie@epa.gov), 703-308-8055. Response to Syngenta's Rebuttal to Plant-back Interval Trinexapac-ethyl End Use Label (Palisade 2EC) and Acceptance Trinexapac-ethyl End Use Label (Palisade EC) and Acceptance Trinexapac-ethyl Technical Label and Letter of Acceptance. Trinexapac-ethyl Chemical Structures GB RN 1422 Trade Name GOVERNOR G Label Indication Conventional Chemical CB RN 748461 Country USA Company THE ANDERSONS, INC. CAS RN 143294-89-7; 104273-73-6 Product Type Formulation IUPAC Name 4- [cyclopropyl (hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylic acid Compound Indication PLANT GROWTH REGULATOR Addresses for mail and hand delivery of objections and hearing requests are provided in 40 CFR 178.25(b). Separated from food and feedstuffs. Pesticide Review Status. Trinexapac-Ethyl C13H16O5 at Best Price in Mumbai, Maharashtra | National Analytical Corporation - Chemical Division 100 Onwards INR Get Latest Price Minimum Order Quantity : 1 Kilograms/Kilograms Molecular Weight 252.26 Grams (g) Molecular Formula C13H16O5 View more details Accepts all Domestic/Foreign inquiries Send Inquiry Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). It does not represent any guarantee of the properties of the product. In 2022, the global top five. Based on these risk assessments, EPA concludes that there is a reasonable certainty that no harm will result to the general population, or to infants and children from aggregate exposure to trinexapac-ethyl residues. There are clear NOAELs/LOAELs for this effect; in which the NOAEL dose is 10-fold lower than the LOAEL dose at which neuropathology is observed, and is therefore sufficiently protective. by the Patent and Trademark Office Finally, EPA has concluded that trinexapac-ethyl is not expected to pose a cancer risk, given the lack of evidence of carcinogenicity in the database. Trinexapac-ethyl, TMS derivative. Be sure to consider the method of trinexapac-ethyl application when trying to maximize effectiveness. DEEMTM 7.81 default concentration factors were used to estimate residues of trinexapac-ethyl in processed commodities. Application of Palisade or Palisade plus Tilt increased grain yield at Chickasha and had no effect on grain yield at Stillwater or Perkins. . This chemical is managed as part of a group or group(s). [Reserved], (c) Tolerances with regional registrations. The trinexapac-ethyl changes the size of the corn p lants, enabling new spatial arrangements. Trade Capacity. Information about this document as published in the Federal Register. Handling in a well ventilated place. Please note that, to comply with Canada's . 02/28/2023, 159 Box 18300, Greensboro, NC 27419. 3501 et seq., nor does it require any special considerations under Executive Order 12898, entitled Federal Actions to Address Environmental Justice in Minority Populations and Low-Income Populations (59 FR 7629, February 16, 1994). daily Federal Register on FederalRegister.gov will remain an unofficial LOC for MOE = 100. Trinexapac-ethyl is a synthetic plant growth regulator that is derived from cyclohexanecarboxylate. Most requests are made by state . In general. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Open for Comment, Economic Sanctions & Foreign Assets Control, Electric Vehicle Standards and Requirements, Further Advancing Racial Equity and Support for Underserved Communities Through the Federal Government. Compliance with the tolerance levels specified below is to be determined by measuring both trinexapac-ethyl, ethyl 4-(cyclopropylhydroxymethylene)-3,5-dioxocyclohexanecarboxylate and the associated metabolite, trinexpac, 4-(cyclopropylhydroxymethylene)-3,5-dioxocyclohexanecarboxylic acid, calculated as the stoichiometric equivalent of trinexapac-ethyl, in or on the commodity. iii. Relevant information about this document from Regulations.gov provides additional context. We are conducting the same trial in 2014 along with a separate trial evaluating Palisade in drought stress environments that is partially funded by Syngenta. Trinexapac-ethyl. on We included an untreated check and ALL plots, including the check, received 10.5 oz/ac of Quilt Xcel at Feekes GS 10.5 (heading). Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. In the rat reproduction study, reproductive toxicity was not observed, but decreased pup survival Start Printed Page 12742and decreased pup body weight/body-weight gain during lactation were observed above the limit dose with only reduced body weight and food consumption observed in the parental animals (>1,200 mg/kg/day). 02/28/2023, 239 The 90-day subchronic dog study showed decreased body weight gain and food consumption, diffuse thymic atrophy, and changes in the epithelial cells of the renal tubules at 516/582 milligrams/kilogram/day (mg/kg/day) (males/females). on Application of Palisade plus Tilt reduced lodging over Palisade alone at Chickasha. Registration Trinexapac-ethyl is a plant hormone , a plant growth regulator. Quick Resources. Dietary Exposure Evaluation Model (DEEMTM) 7.81 default concentration factors were used to estimate residues of trinexapac-ethyl in processed commodities. Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken.If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s).Carrier solvents used in commercial formulations may change physical and toxicological properties.The technical product is a yellow-brown liquid. Sign in to access your AXS Fan Account to manage your tickets. Similar lesions were not observed in the rat or mouse following acute, subchronic or chronic dietary exposure, and there was no other evidence in any other species tested to indicate a neurotoxicity potential. 2015. 801 et seq. As those sections continue to reflect the Agency's current position on those topics, those sections are incorporated here by reference. ).However, the seed yield responses of annual ryegrass (Lolium multiflorum Lam.) Inquiry Basket () February,13th,2023; Hebei Luantong trade.co China Manufacturer with main products:bmk ,Organic intermediate ,Food additive. Developmental toxicity was observed in the rat (increased incidence of asymmetrical sternebrae) and rabbit (decreased number of live fetuses/litter and increased post-implantation loss) at the highest dose tested, with no evidence of maternal toxicity observed in either species. 804(2). Information not marked confidential pursuant to 40 CFR part 2 may be disclosed publicly by EPA without prior notice. As such, the Agency has determined that this action will not have a substantial direct effect on States or Tribal Governments, on the relationship between the National Government and the States or Tribal Governments, or on the distribution of power and responsibilities among the various levels of government or between the Federal Government and Indian Tribes. The documents posted on this site are XML renditions of published Federal It is not an official legal edition of the Federal In adult animals (rats, rabbits, mice, dogs), no systemic adverse effects are seen below the limit dose following subchronic or chronic oral exposure with the exception of dogs. EPA's exposure assessments have been updated to include the additional exposure from the increased tolerance of trinexapac-ethyl from use in or on sugarcane, cane and sugarcane, molasses. It is not an official legal edition of the Federal headings within the legal text of Federal Register documents. 321(q), 346a and 371. ii. documents in the last year, 20 The Agency understands the commenter's concerns and recognizes that some individuals believe that pesticides should be banned completely. documents in the last year, 37 documents in the last year, by the Federal Highway Administration LOAEL = 357 mg/kg/day, based on elevated serum cholesterol values in females, mucoid feces in females and bloody feces in both sexes, and minimal, focal vacuolation of the dorsal medial hippocampus and/or lateral midbrain in both sexes. 346a(d)(3), announcing the filing of a pesticide petition (PP 9F8761) by Syngenta Crop Protection, LLC, P.O. 11/03/2020 at 8:45 am. It is used to control the growth on various grass species and crops. Information about this document as published in the Federal Register. EPA's aggregate exposure assessment incorporated this additional dietary exposure, as well as exposure in drinking water and from residential sources, although those latter exposures are not impacted by the modified use on sugarcane and thus have not changed since the last assessment. publication in the future. Trinexapac-ethyl is classified as "Not likely to be carcinogenic to humans." The combined chronic toxicity/carcinogenicity study in the rat did not demonstrate an increase in any tumor type that would be relevant to humans. ResearchAndMarkets.com Laura Wood, Senior Manager press@researchandmarkets.com For E.S.T Office Hours Call 1-917-300-0470 For U.S./CAN Toll Free Call 1-800-526-8630 For GMT Office Hours . . To summarize our work, we found a trend for one to two inch reductions in plant height when Palisade or Palisade plus Tilt were applied, but this did not consistently translate to increased grain yield. Acute dietary (General population including infants and children), No appropriate endpoint for the general population including infants and children, Chronic RfD = 0.32 mg/kg/day cPAD = 0.32 mg/kg/day. documents in the last year, 662 (a) General. Quantitative acute dietary exposure and risk assessments are performed for a food-use pesticide, if a toxicological study has indicated the possibility of an effect of concern Start Printed Page 12743occurring as a result of a 1-day or single exposure. The acute toxicity of trinexapac-ethyl is low via the oral, eye, dermal, or inhalation routes of exposure, and it is not a dermal sensitizer. In the Federal Register of March 3, 2020 (85 FR 12454) (FRL-10005-58), EPA issued a document pursuant to FFDCA section 408(d)(3), 21 U.S.C. on Health Canada will accept written comments on PRD2020-13 up to 45 days from the date of publication of PRD2020-13. Residues were extracted from wheat with acetonitrile in aqueous phosphate buffer (pH 7) overnight. Based upon review of the data supporting the petition, EPA has revised most of the proposed tolerance levels, added tolerances for hog fat and meat, and deleted the proposed tolerance for cattle kidney. The President of the United States issues other types of documents, including but not limited to; memoranda, notices, determinations, letters, messages, and orders. S-4400, One Potomac Yard (South Bldg. This regulation is effective March 2, 2012. Fresh air, rest. and services, go to from 47 agencies. 4. In making its tolerance decisions, EPA seeks to harmonize U.S. tolerances with international standards whenever possible, consistent with U.S. food safety standards and agricultural practices. offers a preview of documents scheduled to appear in the next day's legal research should verify their results against an official edition of By inhibiting gibberellin, trinexapac-ethyl treatment reduces plant height thereby reducing the tendency to lean or fall over. Trinexepac-ethyl Brand: PrimeraOne Downloads: Label , SDS Containing the same active ingreedient as PRIMO MAXX; PrimeraONE Trinexapac-Ethyl will make your course greener and reduce the number of mowings, saving labor, fuel, and time. How can I get electronic access to other related information? The reasons for these changes are explained in Unit IV.D. In this Issue, Documents 4. Palisade is a giberellic acid inhibitor and works primarily by reducing plant height. The literature also shows that reduction in lodging is relative to the straw strength of the variety. As such, the Agency has determined that this action will not have a substantial direct effect on States or tribal governments, on the relationship between the national government and the States or tribal governments, or on the distribution of power and responsibilities among the various levels of government or between the Federal Government and Indian tribes. iii. documents in the last year, 861 Therefore, an additional 10x database UF was not retained for lack of inhalation toxicity data and these data are not being required. Receipt of a Pesticide Petition Filed for Residues of B. Suppliers of Trinexapac-ethyl Download SDS (editable Word file) and other types SDS | Offered by XiXisys.com SAFETY DATA SHEETS According to the UN GHS revision 8 Version: 1.0 Creation Date: July 15, 2019 Revision Date: July 15, 2019 SECTION 1: Identification 1.1 GHS Product identifier Product name About the Federal Register Cancer. Superintendents across the Southeast are looking for ways to maintain their golf course with fewer staff members. Seed weight was generally inversely related to yield; trinexapac-ethyl treatments that produced the highest yield also had the lowest seed weight. documents in the last year, by the Federal Communications Commission B. Potentially affected entities may include, but are not limited to those engaged in the following activities: This listing is not intended to be exhaustive, but rather to provide a guide for readers regarding entities likely to be affected by this action. Information not marked confidential pursuant to 40 CFR part 2 may be disclosed publicly by EPA without prior notice. In making its tolerance decisions, EPA seeks to harmonize U.S. tolerances with international standards whenever possible, consistent with U.S. food safety standards and agricultural practices. Molecular Formula CHO. Register (ACFR) issues a regulation granting it official legal status. menu. documents in the last year, 822 That is, a plant growth regulator will not make a lodging prone variety stand like one with excellent straw strength, rather they will make it less prone to lodging relative to the same variety non treated. For hazards that have a threshold below which there is no appreciable risk, the toxicological POD is used as the basis for derivation of reference values for risk assessment. This final rule establishes tolerances under section 408(d) of FFDCA in response to petitions submitted to the Agency. Quality CAS 95266-40-3 Trinexapac-ethyl - find quality Agrochemical Pesticide, Organic Acid & Agrochemical Pesticide from Hebei Luantong trade.co of China Suppliers - 168640825. . hb```paB K>K:5R e-b The plant growth regulator trinexapac-ethyl (TE) is widely used to increase seed yield by reducing lodging in many grass species, including perennial ryegrass (Lolium perenne L.) and tall fescue (Festuca arundinacea Schreb. For non-threshold risks, the Agency assumes that any amount of exposure will lead to some degree of risk. Because this final rule has been exempted from review under Executive Order 12866, this final rule is not subject to Executive Order 13211, entitled Actions Concerning Regulations That Significantly Affect Energy Supply, Distribution, or Use (66 FR 28355, May 22, 2001) or Executive Order 13045, entitled Protection of Children from Environmental Health Risks and Safety Risks (62 FR 19885, April 23, 1997). Handle in accordance with good industrial hygiene and safety practice. There are no residual uncertainties in the exposure database. Key words: Leaf architecture, yield components, plant growth, plant growth regulator, Zea mays L. Pesticide manufacturing (NAICS code 32532). These can be useful documents in the last year, 36 (b) Section 18 emergency exemptions. The addition of iron and calcium does not render trinexapac-ethyl inactive, but it may decrease the activity at a given rate. Acting Director, Registration Division, Office of Pesticide Programs. 95266-40-3. documents in the last year, 37 on Compliance with the tolerance levels specified below is to be determined by measuring only the free and conjugated forms of both trinexapac-ethyl, ethyl 4-(cyclopropylhydroxymethylene)-3,5-dioxocyclohexanecarboxylate and trinexapac, 4-(cyclopropylhydroxymethylene)-3,5-dioxocyclohexanecarboxylic acid, calculated as the stoichiometric equivalent . In laboratory experiments with annual . Information on this page: Gas Chromatography; [FR Doc. Compliance with the tolerance levels specified below is to be determined by measuring only the free and conjugated forms of both trinexapac-ethyl, ethyl 4-(cyclopropylhydroxymethylene)-3,5-dioxocyclohexanecarboxylate and trinexapac, 4-(cyclopropylhydroxymethylene)-3,5-dioxocyclohexanecarboxylic acid, calculated as the stoichiometric equivalent of trinexapac-ethyl, in or on the commodity. EPA's assessment of exposures and risks associated with trinexapac-ethyl follows. Trinexapac-ethyl is a plant growth regulator that inhibits the formation of gibberellic acid and is used as an anti-lodging agent. Quick Resources. EPA has evaluated the available toxicity data and considered its validity, completeness, and reliability as well as the relationship of the results of the studies to human risk. Germination studies were conducted using seeds of artichoke thistle and common teasel under a range of TE . III. 21 U.S.C. 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